A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest?

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest?

WebMar 25, 2024 · Cardiac arrest (CA) is a critical public health issue affecting more than half a million Americans annually. The main determinant of outcome post-CA is hypoxic–ischemic brain injury (HIBI), and temperature control is currently the only evidence-based, guideline-recommended intervention targeting secondary brain injury. Temperature control is a key … WebAug 8, 2024 · Research article: Perkins GD, Ji C, Deakin CD, et al. A randomized trial of epinephrine in out-of-hospital cardiac arrest. N Engl J Med.July 18, 2024. [Epub ahead of print.] Full text available here. 40 algorithms every programmer should WebMar 26, 2024 · Trial of Continuous Compressions versus Standard CPR in Patients with Out-Of-Hospital Cardiac Arrest (CCC Protocol) 2011-01-24 Final DSMB Version - … WebBackground: Trans-nasal evaporative cooling is an effective method to induce intra-arrest therapeutic hypothermia in out-of-hospital cardiac arrest (OHCA). The use of … best free windows optimizer 2022 WebAug 11, 2024 · The association of epinephrine with outcomes from out-of-hospital cardiac arrest (OHCA) remains poorly understood, despite epinephrine being routinely used in cardiac arrest resuscitation for more than 50 years. Randomized clinical trial1 evidence has shown that epinephrine increases initial... WebJan 8, 2024 · For decades the standard of care has been to use epinephrine in out of hospital cardiac arrest. There has long been a thought that it reduces mortality by improving rates of return of spontaneous circulation (ROSC). Indeed, the AHA states in the ACLS guidelines that “Standard-dose epinephrine (1 mg every 3 to 5 minutes) may be … 40 algorithms WebResult: In current systematic review and meta-analysis of randomized trials investigating epinephrine for out of hospital cardiac arrest, we found that epinephrine was associated with a significantly higher likelihood of ROSC (RR = 3.05, I 2 = 23.1%, P = .0001) and survival to hospital discharge (RR = 1.40, I 2 = 36.3%, P = .008) compared with ...

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